Most ligand-protein docking programs, including GOLD, are not suitable for docking proteins to other proteins because the problems that must be solved when docking proteins are sufficiently different from those when docking ligands. In particular GOLD requires a distinct concave binding site to be defined, whereas many protein binding interfaces do not have strong concavity.
Was this article helpful?
That’s Great!
Thank you for your feedback
Sorry! We couldn't be helpful
Thank you for your feedback
Feedback sent
We appreciate your effort and will try to fix the article