The most likely cause of this type of problem is that your http server has not been correctly configured to distribute IsoStar scatterplots as mime type chemical/x-isostar. Instead, they are being sent as plain text files, which your browser automatically displays itself, rather than launching the IsoStar client.
For Apache servers, ensure that your mime.types configuration file has the following entry:
chemical/x-isostar istr
For other http servers, locate the appropriate file that configures mime types and edit in a similar manner.
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